Found 32 matching trials
A Study to Determine the Relative Oral Bioavailability of Single Dose Administration of TMC207, Under Fed and Fasted Conditions in Healthy Participants PHASE1 The purpose of this study is to determine the relative oral bioavailability...
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Multiple Locations
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Evaluation of Early Bactericidal Activity and Safety in Pulmonary Tuberculosis With WX-081 PHASE2 This is a multi-center, randomized, parallel, open-label, positive-controll...
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Beijing Chest Hospital affiliated to Capital Medical University
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Linezolid Dosing Strategies in Drug-Resistant TB PHASE2 The purpose of the study was to evaluate the efficacy (how well the medicin...
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Gaborone CRS (Site ID: 12701)
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A Study of TMC207 in Patients With Moderately Impaired Hepatic Function PHASE1 The purpose of this study is to assess the pharmacokinetics (what the body ...
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Multiple Locations
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Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for Drug-sensitive Tuberculosis PHASE2 The current standard management strategy for drug-sensitive pulmonary tuber...
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National Institute of TB and Respiratory Diseases
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A Study of Ultrashort PRS Regimen V in the Treatment of MDR-TB PHASE4 This is an exploratory, prospective, randomized, active control, and open l...
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Shanghai Pulmonary Hospital
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Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB PHASE2 The UNITE4TB consortium is a group of universities and pharmaceutical compa...
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PMSI Institute of Pneumology "Chiril Draganiuc"
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Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis PHASE3 To evaluate the efficacy, safety and tolerability of various doses and dura...
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National Center for Tuberculosis and Lung Diseases
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Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary Tuberculosis PHASE2 The goal of this clinical trial is to evaluate 3 dose levels of TBAJ876 for...
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Active Not Recruiting
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National Center for Tuberculosis and Lung Diseases
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A Study of Bedaquiline 100 Milligram (mg) Tablets Administered as Different Test Formulations Compared to the Commercial Tablet Formulation (F001) in Healthy Adult Participants PHASE1 The purpose of this study is to assess the rate and extent of absorption of...
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SGS Life Science Services
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